	The GeneCascade Software Suite Charité - Universitätsmedizin Berlin & Berliner Institut für Gesundheitsforschung


We are currently updating and restructuring our infrastructure. Our software will be temporarily unavailable during this time.
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MutationTaster2021

taste the disease-causing flavour of different mutations (2021 version for GRCh37)

MutationTaster2026

taste the disease-causing flavour of different mutations (2026 version for GRCh38)

MutationDistiller

combine genotype and phenotype to find the disease-causing mutation

AutozygosityMapper

identify disease-mutations in consanguineous families

HomozygosityMapper

detect the disease-linked region in a homozygosity mapping project

FABIAN-variant

predict the effects of DNA variants on transcription factor binding

FABIAN-variant 2026

improved prediction of the effects of DNA variants on transcription factor binding

SAMS

Symptom Annotation Made Simple

GenDaB

a database for human genes

DrawPed

draw pedigree charts online

RegulationSpotter

spot regulatory alterations when sequencing whole genomes

Team

find out who's behind the GeneCascade

Internship Opportunities

learn more about internship opportunities in our group

Impressum

Deprecated Applications

CNV Inspector

inspect copy number variants

GeneDistiller

distil your disease gene from a sea of candidates

Please use GenDaB instead.

ePOSSUM

assess variation in transcription factor binding sites

Please use FABIAN-variant instead.

MutationTaster 2

a previous version of MutationTaster

Please use MutationTaster2021 or 2026 instead.